• Human FRZB (Frizzled Related Protein) Sandwich ELISA Kit Ready-To-Use (STJE0015359)

Human FRZB (Frizzled Related Protein) Sandwich ELISA Kit Ready-To-Use (STJE0015359)

SKU:
STJE0015359

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 12.9pg/mL
Detection Limit: 31.2-2000pg/mL
Short Description: This FRZB Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: FRZB
Gene ID: 2487
Uniprot ID: SFRP3_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Expressed primarily in the cartilaginous cores of the long bone during embryonic and fetal development and in the appendicular skeleton (6-13 weeks). At 13 weeks of gestation, transcripts were present in early chondroblasts of the tarsal bones of the foot, the carpal bones of the hands and the epiphysis of long bones. Highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. Weakly expressed in lung and liver.
Post Translational Modifications
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.
Protein Name Secreted Frizzled-Related Protein 3
Sfrp-3
Frezzled
Fritz
Frizzled-Related Protein 1
Frzb-1
Database Links
Cellular Localisation Secreted
Alternative ELISA Names Secreted Frizzled-Related Protein 3 ELISA kit
Sfrp-3 ELISA kit
Frezzled ELISA kit
Fritz ELISA kit
Frizzled-Related Protein 1 ELISA kit
Frzb-1 ELISA kit
FRZB ELISA kit
FIZ ELISA kit
FRE ELISA kit
FRP ELISA kit
FRZB1 ELISA kit
SFRP3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance