• Human FPR2 (N-formyl peptide receptor 2) CLIA Kit (STJC0000660)

Human FPR2 (N-formyl peptide receptor 2) CLIA Kit (STJC0000660)

SKU:
STJC0000660

Shipping:
Free Shipping
Current Stock:
Applications: CLIA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 9.38pg/mL
Detection Limit: 15.63~1000pg/mL
Short Description: This human FPR2 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: FPR2
Gene ID: 2358
Uniprot ID: FPR2_HUMAN
Specificity: This kit recognizes Human FPR2 in samples. No significant cross-reactivity or interference between Human FPR2 and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Tissue Specificity Detected in lung, bone marrow, neutrophils, spleen and testis.
Function Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of pro-inflammatory signals such as LTB4 (leukotriene B4). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation. Acts as a receptor for humanin.
Protein Name N-Formyl Peptide Receptor 2
Fmlp-Related Receptor I
Fmlp-R-I
Formyl Peptide Receptor-Like 1
Hm63
Lipoxin A4 Receptor
Lxa4 Receptor
Rfp
Database Links Reactome: R-HSA-416476
Reactome: R-HSA-418594
Reactome: R-HSA-444473
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Associates With Amyloid-Beta Protein 42
Product Of App
At The Cell Surface And The Complex Is Then Rapidly Internalized
Also Internalized In The Presence Of Humanin
Alternative CLIA Names N-Formyl Peptide Receptor 2 CLIA kit
Fmlp-Related Receptor I CLIA kit
Fmlp-R-I CLIA kit
Formyl Peptide Receptor-Like 1 CLIA kit
Hm63 CLIA kit
Lipoxin A4 Receptor CLIA kit
Lxa4 Receptor CLIA kit
Rfp CLIA kit
FPR2 CLIA kit
FPRH1 CLIA kit
FPRL1 CLIA kit
LXA4R CLIA kit
Specificity This kit recognizes Human FPR2 in samples. No significant cross-reactivity or interference between Human FPR2 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 99-116 107
EDTA plasma(n=8) 83-97 90
Cell culture media(n=8) 99-116 107

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (pg/mL) 47.07 114.53 429.70 47.94 104.56 397.60
Standard deviation 4.52 11.11 44.86 4.52 7.47 28.43
CV (%) 9.60 9.70 10.44 9.43 7.14 7.15
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance