| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.064ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This FOLR2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
FOLR2 |
| Gene ID: |
2350 |
| Uniprot ID: |
FOLR2_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues. |
| Post Translational Modifications | N-glycosylated. |
| Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. |
| Protein Name | Folate Receptor BetaFr-BetaFolate Receptor 2Folate Receptor - Fetal/PlacentalPlacental Folate-Binding ProteinFbp |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196757 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecreted |
| Alternative ELISA Names | Folate Receptor Beta ELISA kitFr-Beta ELISA kitFolate Receptor 2 ELISA kitFolate Receptor - Fetal/Placental ELISA kitPlacental Folate-Binding Protein ELISA kitFbp ELISA kitFOLR2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
