| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.071ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This FN3K Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
FN3K |
| Gene ID: |
64122 |
| Uniprot ID: |
FN3K_HUMAN |
| Sample Type: |
plasma, tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Widely expressed. Expressed in erythrocytes. |
| Post Translational Modifications | |
| Function | Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines. |
| Protein Name | Fructosamine-3-KinaseProtein-Psicosamine 3-Kinase Fn3kProtein-Ribulosamine 3-Kinase Fn3k |
| Database Links | Reactome: R-HSA-163841 |
| Cellular Localisation | |
| Alternative ELISA Names | Fructosamine-3-Kinase ELISA kitProtein-Psicosamine 3-Kinase Fn3k ELISA kitProtein-Ribulosamine 3-Kinase Fn3k ELISA kitFN3K ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
