• Human FKBP4 (FK506 Binding Protein 4) Sandwich ELISA Kit Ready-To-Use (STJE0015312)

Human FKBP4 (FK506 Binding Protein 4) Sandwich ELISA Kit Ready-To-Use (STJE0015312)

SKU:
STJE0015312

£481.50 - £659.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.057ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This FKBP4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: FKBP4
Gene ID: 2288
Uniprot ID: FKBP4_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Widely expressed.
Post Translational Modifications Phosphorylation by CK2 results in loss of HSP90 binding activity.
Function Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
Protein Name Peptidyl-Prolyl Cis-Trans Isomerase Fkbp4
Ppiase Fkbp4
51 Kda Fk506-Binding Protein
Fkbp51
52 Kda Fk506-Binding Protein
52 Kda Fkbp
Fkbp-52
59 Kda Immunophilin
P59
Fk506-Binding Protein 4
Fkbp-4
Fkbp59
Hsp-Binding Immunophilin
Hbi
Immunophilin Fkbp52
Rotamase Cleaved Into - Peptidyl-Prolyl Cis-Trans Isomerase Fkbp4 - N-Terminally Processed
Database Links Reactome: R-HSA-3371497
Reactome: R-HSA-3371568
Reactome: R-HSA-8939211
Reactome: R-HSA-9018519
Reactome: R-HSA-9679191
Cellular Localisation Cytoplasm
Cytosol
Mitochondrion
Nucleus
Cytoskeleton
Cell Projection
Axon
Shuttles From Mitochondria To Nucleus
Co-Localizes In Mitochondria With The Glucocorticoid Receptor
Colocalized With Mapt/Tau In The Distal Part Of The Primary Cortical Neurons
Alternative ELISA Names Peptidyl-Prolyl Cis-Trans Isomerase Fkbp4 ELISA kit
Ppiase Fkbp4 ELISA kit
51 Kda Fk506-Binding Protein ELISA kit
Fkbp51 ELISA kit
52 Kda Fk506-Binding Protein ELISA kit
52 Kda Fkbp ELISA kit
Fkbp-52 ELISA kit
59 Kda Immunophilin ELISA kit
P59 ELISA kit
Fk506-Binding Protein 4 ELISA kit
Fkbp-4 ELISA kit
Fkbp59 ELISA kit
Hsp-Binding Immunophilin ELISA kit
Hbi ELISA kit
Immunophilin Fkbp52 ELISA kit
Rotamase Cleaved Into - Peptidyl-Prolyl Cis-Trans Isomerase Fkbp4 - N-Terminally Processed ELISA kit
FKBP4 ELISA kit
FKBP52 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance