| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.109ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This FKBP1A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
FKBP1A |
| Gene ID: |
2280 |
| Uniprot ID: |
FKB1A_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1aPpiase Fkbp1a12 Kda Fk506-Binding Protein12 Kda FkbpFkbp-12Calstabin-1Fk506-Binding Protein 1aFkbp-1aImmunophilin Fkbp12Rotamase |
| Database Links | Reactome: R-HSA-166208Reactome: R-HSA-2025928Reactome: R-HSA-2173789Reactome: R-HSA-2173791Reactome: R-HSA-3656535Reactome: R-HSA-9679191Reactome: R-HSA-9692916 |
| Cellular Localisation | CytoplasmCytosolSarcoplasmic Reticulum MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative ELISA Names | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1a ELISA kitPpiase Fkbp1a ELISA kit12 Kda Fk506-Binding Protein ELISA kit12 Kda Fkbp ELISA kitFkbp-12 ELISA kitCalstabin-1 ELISA kitFk506-Binding Protein 1a ELISA kitFkbp-1a ELISA kitImmunophilin Fkbp12 ELISA kitRotamase ELISA kitFKBP1A ELISA kitFKBP1 ELISA kitFKBP12 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
