Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
15.25pg/mL |
Detection Limit: |
46.8-3000pg/mL |
Short Description: |
This FcgRII Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
FCGR2A |
Gene ID: |
2212 |
Uniprot ID: |
FCG2A_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
serum, plasma or other biological fluids. |
Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-AIgg Fc Receptor Ii-ACdw32Fc-Gamma Rii-AFc-Gamma-RiiaFcrii-ACd Antigen Cd32 |
Database Links | Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-9664323 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative ELISA Names | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A ELISA kitIgg Fc Receptor Ii-A ELISA kitCdw32 ELISA kitFc-Gamma Rii-A ELISA kitFc-Gamma-Riia ELISA kitFcrii-A ELISA kitCd Antigen Cd32 ELISA kitFCGR2A ELISA kitCD32 ELISA kitFCG2 ELISA kitFCGR2A1 ELISA kitIGFR2 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance