| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.055ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This FATP5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
SLC27A5 |
| Gene ID: |
10998 |
| Uniprot ID: |
S27A5_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Predominantly expressed in liver. |
| Post Translational Modifications | |
| Function | May mediate the import of long-chain fatty acids (LCFA) by facilitating their transport across cell membranes. Also catalyzes the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates. Mainly functions as a bile acyl-CoA synthetase catalyzing the activation of bile acids via ATP-dependent formation of bile acid CoA thioesters which is necessary for their subsequent conjugation with glycine or taurine. Both primary bile acids (cholic acid and chenodeoxycholic acid) and secondary bile acids (deoxycholic acid and lithocholic acid) are the principal substrates. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate ((25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate or THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Plays an important role in hepatic fatty acid uptake and bile acid reconjugation and recycling but not in de novo synthesis of bile acids. |
| Protein Name | Long-Chain Fatty Acid Transport Protein 5Fatp-5Fatty Acid Transport Protein 5Bile Acid-Coa LigaseBa-Coa LigaseBalBile Acyl-Coa SynthetaseBacsCholate--Coa LigaseFatty-Acid-Coenzyme A Ligase - Very Long-Chain 3Long-Chain-Fatty-Acid--Coa LigaseSolute Carrier Family 27 Member 5Very Long-Chain Acyl-Coa Synthetase Homolog 2Vlcs-H2Vlcsh2Very Long-Chain Acyl-Coa Synthetase-Related ProteinVlacs-RelatedVlacsr |
| Database Links | Reactome: R-HSA-159418Reactome: R-HSA-193368Reactome: R-HSA-193775 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinMicrosomeCell Membrane |
| Alternative ELISA Names | Long-Chain Fatty Acid Transport Protein 5 ELISA kitFatp-5 ELISA kitFatty Acid Transport Protein 5 ELISA kitBile Acid-Coa Ligase ELISA kitBa-Coa Ligase ELISA kitBal ELISA kitBile Acyl-Coa Synthetase ELISA kitBacs ELISA kitCholate--Coa Ligase ELISA kitFatty-Acid-Coenzyme A Ligase - Very Long-Chain 3 ELISA kitLong-Chain-Fatty-Acid--Coa Ligase ELISA kitSolute Carrier Family 27 Member 5 ELISA kitVery Long-Chain Acyl-Coa Synthetase Homolog 2 ELISA kitVlcs-H2 ELISA kitVlcsh2 ELISA kitVery Long-Chain Acyl-Coa Synthetase-Related Protein ELISA kitVlacs-Related ELISA kitVlacsr ELISA kitSLC27A5 ELISA kitACSB ELISA kitACSVL6 ELISA kitFACVL3 ELISA kitFATP5 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
