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Human ERLIN2 (ER Lipid Raft Associated Protein 2) Sandwich ELISA Kit (STJE0008702)

Human ERLIN2 (ER Lipid Raft Associated Protein 2) Sandwich ELISA Kit (STJE0008702)

Human ERLIN2 (ER Lipid Raft Associated Protein 2) Sandwich ELISA Kit (STJE0008702)

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STJE0008702

£352.50 - £682.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.115ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This ERLIN2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	ERLIN2
Gene ID:	11160
Uniprot ID:	ERLN2_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Ubiquitous.
Post Translational Modifications
Function	Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.
Protein Name	Erlin-2 Endoplasmic Reticulum Lipid Raft-Associated Protein 2 Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2 Spfh Domain-Containing Protein 2
Database Links	Reactome: R-HSA-382556 Reactome: R-HSA-5655302 Reactome: R-HSA-5678895 Reactome: R-HSA-8853336
Cellular Localisation	Endoplasmic Reticulum Membrane Single-Pass Type Ii Membrane Protein Associated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane
Alternative ELISA Names	Erlin-2 ELISA kit Endoplasmic Reticulum Lipid Raft-Associated Protein 2 ELISA kit Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2 ELISA kit Spfh Domain-Containing Protein 2 ELISA kit ERLIN2 ELISA kit C8orf2 ELISA kit SPFH2 ELISA kit UNQ2441 ELISA kit PRO5003 ELISA kit PRO9924 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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