| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.107ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This ERLIN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
ERLIN1 |
| Gene ID: |
10613 |
| Uniprot ID: |
ERLN1_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine. |
| Post Translational Modifications | |
| Function | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex. (Microbial infection) Required early in hepatitis C virus (HCV) infection to initiate RNA replication, and later in the infection to support infectious virus production. |
| Protein Name | Erlin-1Endoplasmic Reticulum Lipid Raft-Associated Protein 1Protein Ke04Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 1Spfh Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-382556Reactome: R-HSA-5678895 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinAssociated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane |
| Alternative ELISA Names | Erlin-1 ELISA kitEndoplasmic Reticulum Lipid Raft-Associated Protein 1 ELISA kitProtein Ke04 ELISA kitStomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 1 ELISA kitSpfh Domain-Containing Protein 1 ELISA kitERLIN1 ELISA kitC10orf69 ELISA kitKE04 ELISA kitKEO4 ELISA kitSPFH1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
