• Human ERAP2 protein (Recombinant) (N-His) (STJP002499)

Human ERAP2 protein (Recombinant) (N-His) (STJP002499)

SKU:
STJP002499-50

£483.50
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Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human ERAP2-N-His protein was developed from hek293 cells and has a target region of N-His. For use in research applications.
Formulation: Supplied as a 0.22 Mu m filtered solution in 12.5mM Tris, 75mM NaCl, pH 7.5, 50% glycercol.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its ability to cleave the fluorogenic peptide substrate, Arg-7-amido-4-methylcoumarin (Arg-AMC). The specific activity is >50 pmoles/min/Mu g.
Gene Symbol: ERAP2
Gene ID: 64167
Uniprot ID: ERAP2_HUMAN
Immunogen Region: Met1-Lys505
Immunogen: Recombinant Human ERAP2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Lys505) of Human ERAP2 (Accession #NP_071745.1) fused with His tag at the N-terminus.
Post Translational Modifications N-glycosylated.
Function Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Protein Name Endoplasmic Reticulum Aminopeptidase 2
Leukocyte-Derived Arginine Aminopeptidase
L-Rap
Database Links Reactome: R-HSA-983170
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Endoplasmic Reticulum Aminopeptidase 2 protein
Leukocyte-Derived Arginine Aminopeptidase protein
L-Rap protein
ERAP2 protein
LRAP protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance