Human ENO1 protein (Recombinant) (N-His) (STJP003756)

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STJP003756
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ENO1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ENO1
Gene ID: 2023
Uniprot ID: ENOA_HUMAN
Immunogen Region: Pro267-Leu354
Immunogen: Homo sapiens (Human)
Post Translational Modifications ISGylated. Lysine 2-hydroxyisobutyrylation (Khib) by p300/EP300 activates the phosphopyruvate hydratase activity.
Function Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. Isoform MBP-1: Binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.
Protein Name Alpha-Enolase
2-Phospho-D-Glycerate Hydro-Lyase
C-Myc Promoter-Binding Protein
Enolase 1
Mbp-1
Mpb-1
Non-Neural Enolase
Nne
Phosphopyruvate Hydratase
Plasminogen-Binding Protein
Database Links Reactome: R-HSA-70171
Reactome: R-HSA-70263
Reactome: R-HSA-9636667
Cellular Localisation Cytoplasm
Cell Membrane
Myofibril
Sarcomere
M Line
Can Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form
Eno1 Is Localized To The M Line
Isoform Mbp-1: Nucleus
Alternative Protein Names Alpha-Enolase protein
2-Phospho-D-Glycerate Hydro-Lyase protein
C-Myc Promoter-Binding Protein protein
Enolase 1 protein
Mbp-1 protein
Mpb-1 protein
Non-Neural Enolase protein
Nne protein
Phosphopyruvate Hydratase protein
Plasminogen-Binding Protein protein
ENO1 protein
ENO1L1 protein
MBPB1 protein
MPB1 protein

Information sourced from Uniprot.org

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