Human EDF1 protein (Recombinant) (N-His) (STJP003327)

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STJP003327
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human EDF1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: EDF1
Gene ID: 8721
Uniprot ID: EDF1_HUMAN
Immunogen Region: Met1-Lys148
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated (by PKA and PKC).
Function Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.
Protein Name Endothelial Differentiation-Related Factor 1
Edf-1
Multiprotein-Bridging Factor 1
Mbf1
Cellular Localisation Cytoplasm
Nucleus
Also Nuclear Upon Binding To Nr5a1 And Treatment Of Cells With Tpa Or Forskolin
Alternative Protein Names Endothelial Differentiation-Related Factor 1 protein
Edf-1 protein
Multiprotein-Bridging Factor 1 protein
Mbf1 protein
EDF1 protein

Information sourced from Uniprot.org

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