| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human DNAM-1/CD226-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
| Immunoreactivity: |
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD226 at 2 Mu g/mL (100 Mu L/well) can bind Recombinant Human CD155 with a linear range of 0.3-1.2 Mu g/mL. |
| Gene Symbol: |
CD226 |
| Gene ID: |
10666 |
| Uniprot ID: |
CD226_HUMAN |
| Immunogen: |
Recombinant Human DNAM-1/CD226 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu19-Asn247) of human CD226 (Accession #NP_006557.2) fused with an Fc, 6×His tag at the C-terminus. |
| Tissue Specificity | Expressed by peripheral blood T-lymphocytes. |
| Function | Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding. |
| Protein Name | Cd226 AntigenDnax Accessory Molecule 1Dnam-1Cd Antigen Cd226 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cd226 Antigen proteinDnax Accessory Molecule 1 proteinDnam-1 proteinCd Antigen Cd226 proteinCD226 proteinDNAM1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
