• Human DGAT1 (Diacylglycerol-O-Acyltransferase Homolog 1) Sandwich ELISA Kit (STJE0008420)

Human DGAT1 (Diacylglycerol-O-Acyltransferase Homolog 1) Sandwich ELISA Kit (STJE0008420)

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STJE0008420

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.114ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This DGAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: DGAT1
Gene ID: 8694
Uniprot ID: DGAT1_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Highly expressed in epithelial cells of the small intestine and its activity is essential for the absorption of dietary fats. In liver, plays a role in esterifying exogenous fatty acids to glycerol, and is required to synthesize fat for storage. Also present in female mammary glands, where it produces fat in the milk. May be involved in VLDL (very low density lipoprotein) assembly. In contrast to DGAT2 it is not essential for survival. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. Exhibits additional acyltransferase activities, includin acyl CoA:monoacylglycerol acyltransferase (MGAT), wax monoester and wax diester synthases. Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG).
Protein Name Diacylglycerol O-Acyltransferase 1
Acat-Related Gene Product 1
Acyl-Coa Retinol O-Fatty-Acyltransferase
Arat
Retinol O-Fatty-Acyltransferase
Diglyceride Acyltransferase
Database Links Reactome: R-HSA-1482883
Reactome: R-HSA-6798695
Reactome: R-HSA-75109
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Diacylglycerol O-Acyltransferase 1 ELISA kit
Acat-Related Gene Product 1 ELISA kit
Acyl-Coa Retinol O-Fatty-Acyltransferase ELISA kit
Arat ELISA kit
Retinol O-Fatty-Acyltransferase ELISA kit
Diglyceride Acyltransferase ELISA kit
DGAT1 ELISA kit
AGRP1 ELISA kit
DGAT ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance