Recombinant Human CXCL14/BRAK Protein was determined by SDS-PAGE with Coomassie Blue, showing bands at 12 kDa.

Human CXCL14/BRAK protein (Recombinant) (C-His) (STJP003065)

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STJP003065
£106.50 - £148.50
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of 0.5 M NaCl, 0.5 M Arginine, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <0.1 EU/Mu g of the protein by LAL method.
Gene Symbol: CXCL14
Gene ID: 9547
Uniprot ID: CXL14_HUMAN
Immunogen Region: Met1-Glu111
Immunogen: Recombinant Human CXCL14/BRAK Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Glu111) of human CXCL14/BRAK (Accession #NP_004878.2) fused with a His tag at the C-terminus.
Immunogen Sequence: SKGHSIRGDNNCTHFPVSQT HMLRELRAAFSQVKTFFQKK DQLDNILLTDSLLQDFKGYL GCQALSEMIKFYLVEVMPQA ENHGPEIKEHLNSLGEKLKT LWIQLRRCHRFLPCENKSKA VEQVKNDFNKLQDKGVYKAM NEFDIFINCIEAYVTLKMKN
Tissue Specificity Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes.
Post Translational Modifications Ubiquitinated, followed by degradation by the proteasome.
Function Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.
Protein Name C-X-C Motif Chemokine 14
Chemokine Brak
Mip-2g
Small-Inducible Cytokine B14
Cellular Localisation Secreted
Alternative Protein Names C-X-C Motif Chemokine 14 protein
Chemokine Brak protein
Mip-2g protein
Small-Inducible Cytokine B14 protein
CXCL14 protein
MIP2G protein
NJAC protein
SCYB14 protein
PSEC0212 protein
UNQ240 protein
PRO273 protein

Information sourced from Uniprot.org

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