Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human CXCL1/GRO-alpha-C-hFC protein was developed from hek293 cells and has a target region of C-hFC. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CXCL1 |
Gene ID: |
2919 |
Uniprot ID: |
GROA_HUMAN |
Immunogen Region: |
Ala35-Asn107 |
Immunogen: |
Recombinant Human CXCL1/GRO-alpha Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala35-Asn107) of human CXCL1/GRO-alpha (Accession #NP_001502.1) fused with and a hFc tag at the C-terminus. |
Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. |
Protein Name | Growth-Regulated Alpha ProteinC-X-C Motif Chemokine 1Gro-Alpha(1-73Melanoma Growth Stimulatory ActivityMgsaNeutrophil-Activating Protein 3Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783Reactome: R-HSA-6798695 |
Cellular Localisation | Secreted |
Alternative Protein Names | Growth-Regulated Alpha Protein proteinC-X-C Motif Chemokine 1 proteinGro-Alpha(1-73 proteinMelanoma Growth Stimulatory Activity proteinMgsa proteinNeutrophil-Activating Protein 3 proteinNap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 proteinCXCL1 proteinGRO proteinGRO1 proteinGROA proteinMGSA proteinSCYB1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance