| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.118ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This CUL9 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
CUL9 |
| Gene ID: |
23113 |
| Uniprot ID: |
CUL9_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Ubiquitously expressed in all tissues with highest expression in testis brain and kidney. |
| Post Translational Modifications | In vitro, self-ubiquitination in the presence of E1, E2 and ubiquitin. Neddylated. |
| Function | Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5. Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function. |
| Protein Name | Cullin-9Cul-9Ubch7-Associated Protein 1P53-Associated Parkin-Like Cytoplasmic Protein |
| Database Links | Reactome: R-HSA-8951664 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Cullin-9 ELISA kitCul-9 ELISA kitUbch7-Associated Protein 1 ELISA kitP53-Associated Parkin-Like Cytoplasmic Protein ELISA kitCUL9 ELISA kitH7AP1 ELISA kitKIAA0708 ELISA kitPARC ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
