• Human CPS1 (Carbamoyl Phosphate Synthase 1, Mitochondrial) Sandwich ELISA Kit Ready-To-Use (STJE0014490)

Human CPS1 (Carbamoyl Phosphate Synthase 1, Mitochondrial) Sandwich ELISA Kit Ready-To-Use (STJE0014490)

SKU:
STJE0014490

£481.50 - £659.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.056ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This CPS1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CPS1
Gene ID: 1373
Uniprot ID: CPSM_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Primarily in the liver and small intestine.
Post Translational Modifications Undergoes proteolytic cleavage in the C-terminal region corresponding to the loss of approximately 12 AA residues from the C-terminus. Succinylated at Lys-287 and Lys-1291. Desuccinylated at Lys-1291 by SIRT5, leading to activation. Glutarylated. Glutarylation levels increase during fasting. Deglutarylated by SIRT5 at Lys-55, Lys-219, Lys-412, Lys-889, Lys-892, Lys-915, Lys-1360 and Lys-1486, leading to activation.
Function Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
Protein Name Carbamoyl-Phosphate Synthase Ammonia - Mitochondrial
Carbamoyl-Phosphate Synthetase I
Cpsase I
Database Links Reactome: R-HSA-70635
Cellular Localisation Mitochondrion
Nucleus
Nucleolus
Cell Membrane
Peripheral Membrane Protein
Extracellular Side
Localizes To The Cell Surface Of Hepatocytes
Alternative ELISA Names Carbamoyl-Phosphate Synthase Ammonia - Mitochondrial ELISA kit
Carbamoyl-Phosphate Synthetase I ELISA kit
Cpsase I ELISA kit
CPS1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance