• Human CPLX2 (Complexin 2) Competitive ELISA Kit (STJE0008105)

Human CPLX2 (Complexin 2) Competitive ELISA Kit (STJE0008105)

SKU:
STJE0008105

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.084ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This CPLX2 Competitive ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 2.5 hrs
Gene Symbol: CPLX2
Gene ID: 10814
Uniprot ID: CPLX2_HUMAN
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia.
Post Translational Modifications
Function Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis.
Protein Name Complexin-2
Complexin Ii
Cpx Ii
Synaphin-1
Database Links
Cellular Localisation Cytoplasm
Cytosol
Presynapse
Nucleus
Perikaryon
Translocated From The Perikaryon To The Presynaptic Terminals During Maturation Of Neuronal Cells
In Mast Cells
Cytosol And Nucleus
Becomes Enriched Near Plasma Membrane Following Stimulation
Alternative ELISA Names Complexin-2 ELISA kit
Complexin Ii ELISA kit
Cpx Ii ELISA kit
Synaphin-1 ELISA kit
CPLX2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance