| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.084ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This CPLX2 Competitive ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
2.5 hrs |
| Gene Symbol: |
CPLX2 |
| Gene ID: |
10814 |
| Uniprot ID: |
CPLX2_HUMAN |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia. |
| Post Translational Modifications | |
| Function | Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis. |
| Protein Name | Complexin-2Complexin IiCpx IiSynaphin-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolPresynapseNucleusPerikaryonTranslocated From The Perikaryon To The Presynaptic Terminals During Maturation Of Neuronal CellsIn Mast CellsCytosol And NucleusBecomes Enriched Near Plasma Membrane Following Stimulation |
| Alternative ELISA Names | Complexin-2 ELISA kitComplexin Ii ELISA kitCpx Ii ELISA kitSynaphin-1 ELISA kitCPLX2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
