• Human CLIC4 (Chloride Intracellular Channel Protein 4) Sandwich ELISA Kit (STJE0007992)

Human CLIC4 (Chloride Intracellular Channel Protein 4) Sandwich ELISA Kit (STJE0007992)

SKU:
STJE0007992

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 30pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This CLIC4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CLIC4
Gene ID: 25932
Uniprot ID: CLIC4_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in epithelial cells from colon, esophagus and kidney (at protein level). Expression is prominent in heart, kidney, placenta and skeletal muscle.
Post Translational Modifications
Function Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).
Protein Name Chloride Intracellular Channel Protein 4
Intracellular Chloride Ion Channel Protein P64h1
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cytoplasmic Vesicle Membrane
Single-Pass Membrane Protein
Nucleus
Cell Membrane
Mitochondrion
Cell Junction
Colocalized With Akap9 At The Centrosome And Midbody
Exists Both As Soluble Cytoplasmic Protein And As Membrane Protein With Probably A Single Transmembrane Domain
Present In An Intracellular Vesicular Compartment That Likely Represent Trans-Golgi Network Vesicles
Might Not Be Present In The Nucleus Of Cardiac Cells
Alternative ELISA Names Chloride Intracellular Channel Protein 4 ELISA kit
Intracellular Chloride Ion Channel Protein P64h1 ELISA kit
CLIC4 ELISA kit
output

Information sourced from Uniprot.org

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