Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.123ng/mL |
Detection Limit: |
0.312-20ng/mL |
Short Description: |
This CLIC1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
CLIC1 |
Gene ID: |
1192 |
Uniprot ID: |
CLIC1_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expression is prominent in heart, placenta, liver, kidney and pancreas. |
Post Translational Modifications | Hydrogen peroxide treatment causes a conformation change, leading to dimerization and formation of an intramolecular disulfide bond between Cys-24 and Cys-59. |
Function | Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. |
Protein Name | Chloride Intracellular Channel Protein 1Chloride Channel AbpNuclear Chloride Ion Channel 27Ncc27Regulatory Nuclear Chloride Ion Channel ProteinHrncc |
Database Links | |
Cellular Localisation | NucleusNucleus MembraneSingle-Pass Membrane ProteinCytoplasmCell MembraneEndoplasmic ReticulumMostly In The Nucleus Including In The Nuclear MembraneSmall Amount In The Cytoplasm And The Plasma MembraneExists Both As Soluble Cytoplasmic Protein And As Membrane Protein With Probably A Single Transmembrane DomainMight Not Be Present In The Nucleus Of Cardiac Cells |
Alternative ELISA Names | Chloride Intracellular Channel Protein 1 ELISA kitChloride Channel Abp ELISA kitNuclear Chloride Ion Channel 27 ELISA kitNcc27 ELISA kitRegulatory Nuclear Chloride Ion Channel Protein ELISA kitHrncc ELISA kitCLIC1 ELISA kitG6 ELISA kitNCC27 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance