Human CLIC1 (Chloride Intracellular Channel Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014366)

Human CLIC1 (Chloride Intracellular Channel Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014366)

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STJE0014366
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.123ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This CLIC1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CLIC1
Gene ID: 1192
Uniprot ID: CLIC1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expression is prominent in heart, placenta, liver, kidney and pancreas.
Post Translational Modifications Hydrogen peroxide treatment causes a conformation change, leading to dimerization and formation of an intramolecular disulfide bond between Cys-24 and Cys-59.
Function In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduces selenite and dehydroascorbate and may act as an antioxidant during oxidative stress response. Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Involved in regulation of the cell cycle.
Protein Name Chloride Intracellular Channel Protein 1
Chloride Channel Abp
Glutaredoxin-Like Oxidoreductase Clic1
Glutathione-Dependent Dehydroascorbate Reductase Clic1
Nuclear Chloride Ion Channel 27
Ncc27
Regulatory Nuclear Chloride Ion Channel Protein
Hrncc
Database Links
Cellular Localisation Nucleus
Nucleus Membrane
Single-Pass Membrane Protein
Cytoplasm
Cell Membrane
Endoplasmic Reticulum
Mostly In The Nucleus Including In The Nuclear Membrane
Small Amount In The Cytoplasm And The Plasma Membrane
Exists Both As Soluble Cytoplasmic Protein And As Membrane Protein With Probably A Single Transmembrane Domain
Might Not Be Present In The Nucleus Of Cardiac Cells
Alternative ELISA Names Chloride Intracellular Channel Protein 1 ELISA kit
Chloride Channel Abp ELISA kit
Glutaredoxin-Like Oxidoreductase Clic1 ELISA kit
Glutathione-Dependent Dehydroascorbate Reductase Clic1 ELISA kit
Nuclear Chloride Ion Channel 27 ELISA kit
Ncc27 ELISA kit
Regulatory Nuclear Chloride Ion Channel Protein ELISA kit
Hrncc ELISA kit
CLIC1 ELISA kit
G6 ELISA kit
NCC27 ELISA kit
output

Information sourced from Uniprot.org

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