• Human CHST15 (Human Carbohydrate Sulfotransferase 15) Sandwich ELISA Kit Ready-To-Use (STJE0014321)

Human CHST15 (Human Carbohydrate Sulfotransferase 15) Sandwich ELISA Kit Ready-To-Use (STJE0014321)

SKU:
STJE0014321

Shipping:
Free Shipping
Current Stock:
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 18.8pg/mL
Detection Limit: 39.6-2500pg/mL
Short Description: This CHST15 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CHST15
Gene ID: 51363
Uniprot ID: CHSTF_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in B-cell-enriched tissues but not in fetal or adult thymus. Expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. Not expressed in T-cells. In pro-B, pre-B, and mature B-cell lines, it colocalizes with RAG1.
Post Translational Modifications Glycosylated.
Function Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression.however such results are unclear in vivo.
Protein Name Carbohydrate Sulfotransferase 15
B-Cell Rag-Associated Gene Protein
Hbrag
N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase
Galnac4s-6st
Database Links Reactome: R-HSA-2022870
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
A Small Fraction May Also Be Present At The Cell Surface
Where It Acts As A B-Cell Receptor
Alternative ELISA Names Carbohydrate Sulfotransferase 15 ELISA kit
B-Cell Rag-Associated Gene Protein ELISA kit
Hbrag ELISA kit
N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase ELISA kit
Galnac4s-6st ELISA kit
CHST15 ELISA kit
BRAG ELISA kit
GALNAC4S6ST ELISA kit
KIAA0598 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance