Human CD38 protein (Recombinant) (N-His) (STJP006602)

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STJP006602
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD38-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CD38
Gene ID: 952
Uniprot ID: CD38_HUMAN
Immunogen Region: Met1-Ile300
Immunogen: Homo sapiens (Human)
Function Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity.
Protein Name Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1
2'-Phospho-Adp-Ribosyl Cyclase
2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase
2'-Phospho-Cyclic-Adp-Ribose Transferase
Adp-Ribosyl Cyclase 1
Adprc 1
Cyclic Adp-Ribose Hydrolase 1
Cadpr Hydrolase 1
T10
Cd Antigen Cd38
Database Links Reactome: R-HSA-196807
Cellular Localisation Cell Surface
Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 protein
2'-Phospho-Adp-Ribosyl Cyclase protein
2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase protein
2'-Phospho-Cyclic-Adp-Ribose Transferase protein
Adp-Ribosyl Cyclase 1 protein
Adprc 1 protein
Cyclic Adp-Ribose Hydrolase 1 protein
Cadpr Hydrolase 1 protein
T10 protein
Cd Antigen Cd38 protein
CD38 protein

Information sourced from Uniprot.org

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