| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human CD20-No tag protein was developed from hek293 cells and has a target region of No tag. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
1.Immobilized Human CD20 VLP at 5 Mu g/ml (100 Mu l/Well) on plate on the plate. Dose response curve for Ofatumumab, hFc Tag with the EC50 of 10.1ng/ml determined by ELISA.2.Immobilized Human CD20 VLP at 5 Mu g/ml (100 Mu l/Well) on plate on the plat |
| Gene Symbol: |
MS4A1 |
| Gene ID: |
931 |
| Uniprot ID: |
CD20_HUMAN |
| Immunogen Region: |
Met1-Pro297 |
| Immunogen: |
Recombinant Human CD20 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro297) of human CD20 (Accession #NP_068769.2) fused with no additional amino acid. |
| Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Protein Name | B-Lymphocyte Antigen Cd20B-Lymphocyte Surface Antigen B1Bp35Leukocyte Surface Antigen Leu-16Membrane-Spanning 4-Domains Subfamily A Member 1Cd Antigen Cd20 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLipid-AnchorConstitutively Associated With Membrane Rafts |
| Alternative Protein Names | B-Lymphocyte Antigen Cd20 proteinB-Lymphocyte Surface Antigen B1 proteinBp35 proteinLeukocyte Surface Antigen Leu-16 proteinMembrane-Spanning 4-Domains Subfamily A Member 1 proteinCd Antigen Cd20 proteinMS4A1 proteinCD20 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
