Post Translational Modifications | The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes. |
Function | May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. |
Protein Name | C-C Motif Chemokine 22Cc Chemokine Stcp-1Mdc(1-69Macrophage-Derived ChemokineSmall-Inducible Cytokine A22Stimulated T-Cell Chemotactic Protein 1 Cleaved Into - Mdc(3-69 - Mdc(5-69 - Mdc(7-69 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783Reactome: R-HSA-6785807 |
Cellular Localisation | Secreted |
Alternative Antibody Pair Names | C-C Motif Chemokine 22 antibody pairCc Chemokine Stcp-1 antibody pairMdc(1-69 antibody pairMacrophage-Derived Chemokine antibody pairSmall-Inducible Cytokine A22 antibody pairStimulated T-Cell Chemotactic Protein 1 Cleaved Into - Mdc(3-69 - Mdc(5-69 - Mdc(7-69 antibody pairCCL22 antibody pairMDC antibody pairSCYA22 antibody pairA-152E5.1 antibody pair |
Information sourced from Uniprot.org