| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
4.55pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This CCK Competitive ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
2.5 hrs |
| Gene Symbol: |
CCK |
| Gene ID: |
885 |
| Uniprot ID: |
CCKN_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | Detected in cerebrospinal fluid and urine (at protein level). |
| Post Translational Modifications | The precursor is cleaved by proteases to produce a number of active cholecystokinins. Cholecystokinin-5: The precursor is cleaved by ACE, which removes the Gly-Arg-Arg peptide at the C-terminus, leading to mature hormone. |
| Function | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. |
| Protein Name | CholecystokininCck Cleaved Into - Cholecystokinin-58Cck58 - Cholecystokinin-58 Desnonopeptide(1-49-Cck58 - Cholecystokinin-39Cck39 - Cholecystokinin-33Cck33 - Cholecystokinin-25Cck25 - Cholecystokinin-18Cck18 - Cholecystokinin-12Cck12 - Cholecystokinin-8Cck8 - Cholecystokinin-7Cck7 - Cholecystokinin-5Cck5 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Cholecystokinin ELISA kitCck Cleaved Into - Cholecystokinin-58 ELISA kitCck58 - Cholecystokinin-58 Desnonopeptide ELISA kit(1-49-Cck58 - Cholecystokinin-39 ELISA kitCck39 - Cholecystokinin-33 ELISA kitCck33 - Cholecystokinin-25 ELISA kitCck25 - Cholecystokinin-18 ELISA kitCck18 - Cholecystokinin-12 ELISA kitCck12 - Cholecystokinin-8 ELISA kitCck8 - Cholecystokinin-7 ELISA kitCck7 - Cholecystokinin-5 ELISA kitCck5 ELISA kitCCK ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
