| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.128ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This CC2D1A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
CC2D1A |
| Gene ID: |
54862 |
| Uniprot ID: |
C2D1A_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation on Ser-208 by CDK1 promotes spindle pole localization and association with SCC1/RAD21. |
| Function | Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis. |
| Protein Name | Coiled-Coil And C2 Domain-Containing Protein 1aAkt Kinase-Interacting Protein 1Five Prime Repressor Element Under Dual Repression-Binding Protein 1Fre Under Dual Repression-Binding Protein 1Freud-1Putative Nf-Kappa-B-Activating Protein 023n |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative ELISA Names | Coiled-Coil And C2 Domain-Containing Protein 1a ELISA kitAkt Kinase-Interacting Protein 1 ELISA kitFive Prime Repressor Element Under Dual Repression-Binding Protein 1 ELISA kitFre Under Dual Repression-Binding Protein 1 ELISA kitFreud-1 ELISA kitPutative Nf-Kappa-B-Activating Protein 023n ELISA kitCC2D1A ELISA kitAKI1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
