• Human CC2D1A (Coiled Coil And C2 Domain Containing Protein 1A) Sandwich ELISA Kit (STJE0007736)

Human CC2D1A (Coiled Coil And C2 Domain Containing Protein 1A) Sandwich ELISA Kit (STJE0007736)

SKU:
STJE0007736

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.128ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This CC2D1A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CC2D1A
Gene ID: 54862
Uniprot ID: C2D1A_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylation on Ser-208 by CDK1 promotes spindle pole localization and association with SCC1/RAD21.
Function Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.
Protein Name Coiled-Coil And C2 Domain-Containing Protein 1a
Akt Kinase-Interacting Protein 1
Five Prime Repressor Element Under Dual Repression-Binding Protein 1
Fre Under Dual Repression-Binding Protein 1
Freud-1
Putative Nf-Kappa-B-Activating Protein 023n
Database Links
Cellular Localisation Cytoplasm
Nucleus
Cytoskeleton
Microtubule Organizing Center
Centrosome
Alternative ELISA Names Coiled-Coil And C2 Domain-Containing Protein 1a ELISA kit
Akt Kinase-Interacting Protein 1 ELISA kit
Five Prime Repressor Element Under Dual Repression-Binding Protein 1 ELISA kit
Fre Under Dual Repression-Binding Protein 1 ELISA kit
Freud-1 ELISA kit
Putative Nf-Kappa-B-Activating Protein 023n ELISA kit
CC2D1A ELISA kit
AKI1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance