• Human Calumenin protein (Recombinant) (C-His) (STJP002471)

Human Calumenin protein (Recombinant) (C-His) (STJP002471)

SKU:
STJP002471

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Calumenin-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.2 Mu m filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CALU
Gene ID: 813
Uniprot ID: CALU_HUMAN
Immunogen Region: Lys20-Phe315
Immunogen: Recombinant Human Calumenin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys20-Phe315) of human Calumenin (Accession #NP_001210.1) fused with a 6×His tag at the C-terminus.
Function Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.
Protein Name Calumenin
Crocalbin
Ief Ssp 9302
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Endoplasmic Reticulum Membrane
Golgi Apparatus
Secreted
Melanosome
Sarcoplasmic Reticulum Lumen
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Protein Names Calumenin protein
Crocalbin protein
Ief Ssp 9302 protein
CALU protein

Information sourced from Uniprot.org

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