| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.62ng/mL |
| Detection Limit: |
1.56-100ng/mL |
| Short Description: |
This C4BPa Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
C4BPA |
| Gene ID: |
722 |
| Uniprot ID: |
C4BPA_HUMAN |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | Chylomicrons in the plasma. |
| Post Translational Modifications | |
| Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
| Protein Name | C4b-Binding Protein Alpha ChainC4bpProline-Rich ProteinPrp |
| Database Links | Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | C4b-Binding Protein Alpha Chain ELISA kitC4bp ELISA kitProline-Rich Protein ELISA kitPrp ELISA kitC4BPA ELISA kitC4BP ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
