Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.053ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This b3GAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
B3GAT1 |
Gene ID: |
27087 |
Uniprot ID: |
B3GA1_HUMAN |
Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Mainly expressed in the brain. |
Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
Protein Name | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1Beta-1 -3-Glucuronyltransferase 1Glucuronosyltransferase PGlcat-PUdp-Glcua -Glycoprotein Beta-1 -3-GlucuronyltransferaseGlcuat-P |
Database Links | Reactome: R-HSA-1971475 |
Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedIsoform 2: Golgi Apparatus MembraneEndoplasmic Reticulum Membrane |
Alternative ELISA Names | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 ELISA kitBeta-1 -3-Glucuronyltransferase 1 ELISA kitGlucuronosyltransferase P ELISA kitGlcat-P ELISA kitUdp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase ELISA kitGlcuat-P ELISA kitB3GAT1 ELISA kitGLCATP ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance