• Human ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator) Sandwich ELISA Kit (STJE0007312)

Human ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator) Sandwich ELISA Kit (STJE0007312)

SKU:
STJE0007312

Shipping:
Free Shipping
Current Stock:
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.067ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This ARNT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ARNT
Gene ID: 405
Uniprot ID: ARNT_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Required for activity of the AHR. Upon ligand binding, AHR translocates into the nucleus, where it heterodimerizes with ARNT and induces transcription by binding to xenobiotic response elements (XRE). Not required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex initiates transcription of genes involved in the regulation of a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation (Probable). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.
Protein Name Aryl Hydrocarbon Receptor Nuclear Translocator
Arnt Protein
Class E Basic Helix-Loop-Helix Protein 2
Bhlhe2
Dioxin Receptor - Nuclear Translocator
Hypoxia-Inducible Factor 1-Beta
Hif-1-Beta
Hif1-Beta
Database Links Reactome: R-HSA-1234158
Reactome: R-HSA-1989781
Reactome: R-HSA-211945
Reactome: R-HSA-211976
Reactome: R-HSA-211981
Reactome: R-HSA-8937144
Reactome: R-HSA-9768919
Cellular Localisation Nucleus
Alternative ELISA Names Aryl Hydrocarbon Receptor Nuclear Translocator ELISA kit
Arnt Protein ELISA kit
Class E Basic Helix-Loop-Helix Protein 2 ELISA kit
Bhlhe2 ELISA kit
Dioxin Receptor - Nuclear Translocator ELISA kit
Hypoxia-Inducible Factor 1-Beta ELISA kit
Hif-1-Beta ELISA kit
Hif1-Beta ELISA kit
ARNT ELISA kit
BHLHE2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance