• Human APAF1 (Apoptotic Peptidase Activating Factor 1) Sandwich ELISA Kit Ready-To-Use (STJE0013578)

Human APAF1 (Apoptotic Peptidase Activating Factor 1) Sandwich ELISA Kit Ready-To-Use (STJE0013578)

SKU:
STJE0013578

£462.50 - £632.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.064ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This APAF1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: APAF1
Gene ID: 317
Uniprot ID: APAF_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.
Post Translational Modifications
Function Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Protein Name Apoptotic Protease-Activating Factor 1
Apaf-1
Database Links Reactome: R-HSA-111458
Reactome: R-HSA-111459
Reactome: R-HSA-111463
Reactome: R-HSA-111464
Reactome: R-HSA-6798695
Reactome: R-HSA-6803207
Reactome: R-HSA-8953750
Reactome: R-HSA-9627069
Cellular Localisation Cytoplasm
Alternative ELISA Names Apoptotic Protease-Activating Factor 1 ELISA kit
Apaf-1 ELISA kit
APAF1 ELISA kit
KIAA0413 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance