• Human ADAM12 (A Disintegrin And Metalloprotease 12) Sandwich ELISA Kit (STJE0006886)

Human ADAM12 (A Disintegrin And Metalloprotease 12) Sandwich ELISA Kit (STJE0006886)

SKU:
STJE0006886

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 28pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This ADAM12 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ADAM12
Gene ID: 8038
Uniprot ID: ADA12_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
Protein Name Disintegrin And Metalloproteinase Domain-Containing Protein 12
Adam 12
Meltrin-Alpha
Database Links Reactome: R-HSA-177929
Reactome: R-HSA-8941237
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Isoform 3: Secreted
Isoform 4: Secreted
Alternative ELISA Names Disintegrin And Metalloproteinase Domain-Containing Protein 12 ELISA kit
Adam 12 ELISA kit
Meltrin-Alpha ELISA kit
ADAM12 ELISA kit
MLTN ELISA kit
UNQ346 ELISA kit
PRO545 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance