• Human ABCG1 (ATP Binding Cassette Transporter G1) Sandwich ELISA Kit (STJE0006828)

Human ABCG1 (ATP Binding Cassette Transporter G1) Sandwich ELISA Kit (STJE0006828)

SKU:
STJE0006828

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.061ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This ABCG1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ABCG1
Gene ID: 9619
Uniprot ID: ABCG1_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in several tissues. Expressed in macrophages.expression is increased in macrophages from patients with Tangier disease.
Post Translational Modifications Palmitoylation at Cys-315 seems important for trafficking from the endoplasmic reticulum.
Function Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol.
Protein Name Atp-Binding Cassette Sub-Family G Member 1
Atp-Binding Cassette Transporter 8
White Protein Homolog
Database Links Reactome: R-HSA-1369062
Reactome: R-HSA-8964058
Reactome: R-HSA-9029569
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Cell Membrane
Predominantly Localized In The Intracellular Compartments Mainly Associated With The Endoplasmic Reticulum (Er) And Golgi Membranes
Alternative ELISA Names Atp-Binding Cassette Sub-Family G Member 1 ELISA kit
Atp-Binding Cassette Transporter 8 ELISA kit
White Protein Homolog ELISA kit
ABCG1 ELISA kit
ABC8 ELISA kit
WHT1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance