| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.062ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This AADAT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
AADAT |
| Gene ID: |
51166 |
| Uniprot ID: |
AADAT_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary. |
| Post Translational Modifications | |
| Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). |
| Protein Name | Kynurenine/Alpha-Aminoadipate Aminotransferase - MitochondrialKat/Aadat2-Aminoadipate Aminotransferase2-Aminoadipate TransaminaseAlpha-Aminoadipate AminotransferaseAadatGlycine Transaminase AadatKynurenine Aminotransferase IiKynurenine--Glyoxylate Transaminase AadatKynurenine--Oxoglutarate Aminotransferase IiKynurenine--Oxoglutarate Transaminase 2Kynurenine--Oxoglutarate Transaminase IiMethionine--Glyoxylate Transaminase Aadat |
| Database Links | Reactome: R-HSA-71064Reactome: R-HSA-71240 |
| Cellular Localisation | Mitochondrion |
| Alternative ELISA Names | Kynurenine/Alpha-Aminoadipate Aminotransferase - Mitochondrial ELISA kitKat/Aadat ELISA kit2-Aminoadipate Aminotransferase ELISA kit2-Aminoadipate Transaminase ELISA kitAlpha-Aminoadipate Aminotransferase ELISA kitAadat ELISA kitGlycine Transaminase Aadat ELISA kitKynurenine Aminotransferase Ii ELISA kitKynurenine--Glyoxylate Transaminase Aadat ELISA kitKynurenine--Oxoglutarate Aminotransferase Ii ELISA kitKynurenine--Oxoglutarate Transaminase 2 ELISA kitKynurenine--Oxoglutarate Transaminase Ii ELISA kitMethionine--Glyoxylate Transaminase Aadat ELISA kitAADAT ELISA kitKAT2 ELISA kitKYAT2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
