Dopamine Receptor D4 Blocking Peptide for STJ500717 peptide (STJ503944)

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STJ503944-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Dopamine Receptor D4 Blocking Peptide for STJ500717 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Drd4
Gene ID: 13491
Uniprot ID: DRD4_MOUSE
Specificity: This blocking peptide is recommended for use in combination with Dopamine Receptor D4 antibody, STJ500717
Immunogen: Synthetic peptide corresponding to unique sequence on Dopamine Receptor D4 protein.
Tissue Specificity Detected in olfactory bulb, hypothalamus, olfactory tubercle, brainstem and striatum.
Post Translational Modifications Palmitoylated. Palmitoylation of the C-terminal Cys is important for normal expression at the cell membrane.
Function Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs. Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells.
Peptide Name D(4 Dopamine Receptor
D(2c Dopamine Receptor
Dopamine D4 Receptor
Database Links Reactome: R-MMU-390651
Reactome: -MMU-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names D(4 Dopamine Receptor protein
D(2c Dopamine Receptor protein
Dopamine D4 Receptor protein
Drd4 protein

Information sourced from Uniprot.org

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