| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ZP4 (400-500) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZP4 |
| Gene ID: |
57829 |
| Uniprot ID: |
ZP4_HUMAN |
| Immunogen Region: |
400-500 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human ZP4 (NP_067009.1). |
| Immunogen Sequence: |
IPVQKALDLPFPSHHQRFSI FTFSFVNPTVEKQALRGPVH LHCSVSVCQPAETPSCVVTC PDLSRRRNFDNSSQNTTASV SSKGPMILLQATKDPPEKLR V |
| Tissue Specificity | Expressed in oocytes. |
| Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. |
| Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor. |
| Protein Name | Zona Pellucida Sperm-Binding Protein 4Zona Pellucida Glycoprotein 4Zp-4Zona Pellucida Protein B Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 4 |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 4: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Zona Pellucida Sperm-Binding Protein 4 antibodyAnti-Zona Pellucida Glycoprotein 4 antibodyAnti-Zp-4 antibodyAnti-Zona Pellucida Protein B Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 4 antibodyAnti-ZP4 antibodyAnti-ZPB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
