| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ZFP42 (1-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZFP42 |
| Gene ID: |
132625 |
| Uniprot ID: |
ZFP42_HUMAN |
| Immunogen Region: |
1-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ZFP42 (NP_777560.2). |
| Immunogen Sequence: |
MSQQLKKRAKTRHQKGLGGR APSGAKPRQGKSSQDLQAEI EPVSAVWALCDGYVCYEPGP QALGGDDFSDCYIECVIRGE FSQPILEEDSLFESLEYLKK GSEQQLSQKVFEASSLECSL EYMKKGVKKELPQKIVGENS |
| Tissue Specificity | Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines. |
| Post Translational Modifications | Polyubiquitinated by RNF12, leading to proteasomal degradation. |
| Function | Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal. |
| Protein Name | Zinc Finger Protein 42 HomologZfp-42Reduced Expression Protein 1Rex-1Hrex-1Zinc Finger Protein 754 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 42 Homolog antibodyAnti-Zfp-42 antibodyAnti-Reduced Expression Protein 1 antibodyAnti-Rex-1 antibodyAnti-Hrex-1 antibodyAnti-Zinc Finger Protein 754 antibodyAnti-ZFP42 antibodyAnti-REX1 antibodyAnti-ZNF754 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
