Anti-ZFP42 antibody (1-140) (STJ118399)

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STJ118399
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZFP42
Gene ID: 132625
Uniprot ID: ZFP42_HUMAN
Immunogen Region: 1-140
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ZFP42 (NP_777560.2).
Immunogen Sequence: MSQQLKKRAKTRHQKGLGGR APSGAKPRQGKSSQDLQAEI EPVSAVWALCDGYVCYEPGP QALGGDDFSDCYIECVIRGE FSQPILEEDSLFESLEYLKK GSEQQLSQKVFEASSLECSL EYMKKGVKKELPQKIVGENS
Tissue Specificity Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines.
Post Translational Modifications Polyubiquitinated by RNF12, leading to proteasomal degradation.
Function Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal.
Protein Name Zinc Finger Protein 42 Homolog
Zfp-42
Reduced Expression Protein 1
Rex-1
Hrex-1
Zinc Finger Protein 754
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Zinc Finger Protein 42 Homolog antibody
Anti-Zfp-42 antibody
Anti-Reduced Expression Protein 1 antibody
Anti-Rex-1 antibody
Anti-Hrex-1 antibody
Anti-Zinc Finger Protein 754 antibody
Anti-ZFP42 antibody
Anti-REX1 antibody
Anti-ZNF754 antibody

Information sourced from Uniprot.org