| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | YKT6 |
| Gene ID: | 10652 |
| Uniprot ID: | YKT6_HUMAN |
| Immunogen Region: | 100-198 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-198 of human YKT6 (NP_006546.1). |
| Immunogen Sequence: | EFSKQVDRIDWPVGSPATIH YPALDGHLSRYQNPREADPM TKVQAELDETKIILHNTMES LLERGEKLDDLVSKSEVLGT QSKAFYKTARKQNSCCAIM |
| Post Translational Modifications | Palmitoylated.catalyzes its own palmitoylation. Palmitoylation is required for Golgi targeting. Farnesylation is required for Golgi targeting. |
| Function | Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport.as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport.as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity. |
| Protein Name | Synaptobrevin Homolog Ykt6 |
| Database Links | Reactome: R-HSA-204005 Reactome: R-HSA-6807878 Reactome: R-HSA-6811438 Reactome: R-HSA-8980692 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 Reactome: R-HSA-9013408 Reactome: R-HSA-9013423 |
| Cellular Localisation | Cytoplasm Cytosol Cytoplasmic Vesicle Membrane Lipid-Anchor Cytoplasmic Side Golgi Apparatus Membrane Probably Cycles Through Vesicles Between Golgi And Endosomes |
| Alternative Antibody Names | Anti-Synaptobrevin Homolog Ykt6 antibody Anti-YKT6 antibody |
Information sourced from Uniprot.org