| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | WDR35 |
| Gene ID: | 57539 |
| Uniprot ID: | WDR35_HUMAN |
| Immunogen Region: | 871-1170 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 871-1170 of human WDR35 (NP_065830.2). |
| Immunogen Sequence: | CSQPKAAVDTCVHLNQWNKA VELAKNHSMKEIGSLLARYA SHLLEKNKTLDAIELYRKAN YFFDAAKLMFKIADEEAKKG SKPLRVKKLYVLSALLIEQY HEQMKNAQRGKVKGKSSEAT SALAGLLEEEVLSTTDRFTD NAWRGAEAYHFFILAQRQLY EGCVDTALKTALHLKDYEDI IPPVEIYSLLALCACASRAF GTCSKAFIKLKSLETLSSEQ KQQYEDLALEIFTKHTSKD |
| Function | As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. May promote CASP3 activation and TNF-stimulated apoptosis. |
| Protein Name | Wd Repeat-Containing Protein 35Intraflagellar Transport Protein 121 Homolog |
| Database Links | Reactome: R-HSA-5610787Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCilium AxonemeCilium Basal Body |
| Alternative Antibody Names | Anti-Wd Repeat-Containing Protein 35 antibodyAnti-Intraflagellar Transport Protein 121 Homolog antibodyAnti-WDR35 antibodyAnti-IFT121 antibodyAnti-KIAA1336 antibody |
Information sourced from Uniprot.org