| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-VSX1 (1-170) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
VSX1 |
| Gene ID: |
30813 |
| Uniprot ID: |
VSX1_HUMAN |
| Immunogen Region: |
1-170 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human VSX1 (NP_055403.2). |
| Immunogen Sequence: |
MTGRDSLSDGRTSSRALVPG GSPRGSRPRGFAITDLLGLE AELPAPAGPGQGSGCEGPAV APCPGPGLDGSSLARGALPL GLGLLCGFGTQPPAAARAPC LLLADVPFLPPRGPEPAAPL APSRPPPALGRQKRSDSVST SDEDSQSEDRNDLKASPTLG KRKKRRHRTV |
| Tissue Specificity | In the adult eye, expressed in lens, iris, ciliary body, choroid, optical nerve head and, most strongly, in retina, but not expressed in sclera and cornea. expressed in adult retina but not in lens and cornea. Within adult retina, found exclusively in the inner nuclear layer. Isoform 1, isoform 2, isoform 3 and isoform 4 expressed in adult retina, but not in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. Not expressed in thymus and spleen. Expressed in embryonic craniofacial tissue. Expressed in fetal (week 14) retina. Strongly expressed in neonatal retina, weakly in neonatal lens, choroid and cornea (day 1, 4.month 9). |
| Function | Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development. Dispensable in early retinal development. |
| Protein Name | Visual System Homeobox 1Homeodomain Protein RinxRetinal Inner Nuclear Layer Homeobox ProteinTranscription Factor Vsx1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Visual System Homeobox 1 antibodyAnti-Homeodomain Protein Rinx antibodyAnti-Retinal Inner Nuclear Layer Homeobox Protein antibodyAnti-Transcription Factor Vsx1 antibodyAnti-VSX1 antibodyAnti-RINX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
