| Tissue Specificity | In the adult eye, expressed in lens, iris, ciliary body, choroid, optical nerve head and, most strongly, in retina, but not expressed in sclera and cornea. expressed in adult retina but not in lens and cornea. Within adult retina, found exclusively in the inner nuclear layer. Isoform 1, isoform 2, isoform 3 and isoform 4 expressed in adult retina, but not in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. Not expressed in thymus and spleen. Expressed in embryonic craniofacial tissue. Expressed in fetal (week 14) retina. Strongly expressed in neonatal retina, weakly in neonatal lens, choroid and cornea (day 1, 4.month 9). |
| Function | Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development. Dispensable in early retinal development. |
| Protein Name | Visual System Homeobox 1Homeodomain Protein RinxRetinal Inner Nuclear Layer Homeobox ProteinTranscription Factor Vsx1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Visual System Homeobox 1 antibodyAnti-Homeodomain Protein Rinx antibodyAnti-Retinal Inner Nuclear Layer Homeobox Protein antibodyAnti-Transcription Factor Vsx1 antibodyAnti-VSX1 antibodyAnti-RINX antibody |
Information sourced from Uniprot.org
