Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-VRK3 (266-412) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
VRK3 |
Gene ID: |
51231 |
Uniprot ID: |
VRK3_HUMAN |
Immunogen Region: |
266-412 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 266-412 of human VRK3 (NP_001295349). |
Immunogen Sequence: |
LQSALDVSPKHVLSERSVLQ VACRLLDALEFLHENEYVHG NVTAENIFVDPEDQSQVTLA GYGFAFRYCPSGKHVAYVEG SRSPHEGDLEFISMDLHKGC GPSRRSDLQSLGYCMLKWLY GFLPWTNCLPNTEDIMKQKQ KLPWDSF |
Function | Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus. |
Protein Name | Inactive Serine/Threonine-Protein Kinase Vrk3Serine/Threonine-Protein Pseudokinase Vrk3Vaccinia-Related Kinase 3 |
Database Links | Reactome: R-HSA-202670 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Inactive Serine/Threonine-Protein Kinase Vrk3 antibodyAnti-Serine/Threonine-Protein Pseudokinase Vrk3 antibodyAnti-Vaccinia-Related Kinase 3 antibodyAnti-VRK3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance