• Western blot analysis of extracts of various cell lines, using VNN2 antibody (STJ110469) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-VNN2 antibody (270-493) (STJ110469)

SKU:
STJ110469

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-VNN2 (270-493) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: VNN2
Gene ID: 8875
Uniprot ID: VNN2_HUMAN
Immunogen Region: 270-493
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-493 of human VNN2 (NP_004656.2).
Immunogen Sequence: VSLNMTGSGIYAPNGPKVYH YDMKTELGKLLLSEVDSHPL SSLAYPTAVNWNAYATTIKP FPVQKNTFRGFISRDGFNFT ELFENAGNLTVCQKELCCHL SYRMLQKEENEVYVLGAFTG LHGRRRREYWQVCTMLKCKT TNLTTCGRPVETASTRFEMF SLSGTFGTEYVFPEVLLTEI HLSPGKFEVLKDGRLVNKNG SSGPILTVSLFGRWYTKDSL YSSC
Tissue Specificity Widely expressed with higher expression in spleen and blood.
Function Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.
Protein Name Pantetheine Hydrolase Vnn2
Glycosylphosphatidyl Inositol-Anchored Protein Gpi-80
Protein Foap-4
Vascular Non-Inflammatory Molecule 2
Vanin-2
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-199220
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Pantetheine Hydrolase Vnn2 antibody
Anti-Glycosylphosphatidyl Inositol-Anchored Protein Gpi-80 antibody
Anti-Protein Foap-4 antibody
Anti-Vascular Non-Inflammatory Molecule 2 antibody
Anti-Vanin-2 antibody
Anti-VNN2 antibody

Information sourced from Uniprot.org

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