| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UROD |
| Gene ID: | 7389 |
| Uniprot ID: | DCUP_HUMAN |
| Immunogen Region: | 1-367 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-367 of human UROD (NP_000365.3). |
| Immunogen Sequence: | MEANGLGPQGFPELKNDTFL RAAWGEETDYTPVWCMRQAG RYLPEFRETRAAQDFFSTCR SPEACCELTLQPLRRFPLDA AIIFSDILVVPQALGMEVTM VPGKGPSFPEPLREEQDLER LRDPEVVASELGYVFQAITL TRQRLAGRVPLIGFAGAPWT LMTYMVEGGGSSTMAQAKRW LYQRPQASHQLLRILTDALV PYLVGQVVAGAQALQLFESH AGHLGPQLFNKFALPYIRD |
| Function | Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I. |
| Protein Name | Uroporphyrinogen DecarboxylaseUpdUro-D |
| Database Links | Reactome: R-HSA-189451 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Uroporphyrinogen Decarboxylase antibodyAnti-Upd antibodyAnti-Uro-D antibodyAnti-UROD antibody |
Information sourced from Uniprot.org