| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000IHC-P:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ULBP1 |
| Gene ID: | 80329 |
| Uniprot ID: | ULBP1_HUMAN |
| Immunogen Region: | 26-216 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human ULBP1 (NP_079494.1). |
| Immunogen Sequence: | GWVDTHCLCYDFIITPKSRP EPQWCEVQGLVDERPFLHYD CVNHKAKAFASLGKKVNVTK TWEEQTETLRDVVDFLKGQL LDIQVENLIPIEPLTLQARM SCEHEAHGHGRGSWQFLFNG QKFLLFDSNNRKWTALHPGA KKMTEKWEKNRDVTMFFQKI SLGDCKMWLEEFLMYWEQML DPTKPPSLAPG |
| Tissue Specificity | Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver. |
| Function | Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. |
| Protein Name | Ul16-Binding Protein 1Alcan-BetaNkg2d Ligand 1N2dl-1Nkg2dl1Retinoic Acid Early Transcript 1i |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorEndoplasmic ReticulumIn Cmv-Infected FibroblastsDetected In The Endoplasmic Reticulum/Cis-Golgi |
| Alternative Antibody Names | Anti-Ul16-Binding Protein 1 antibodyAnti-Alcan-Beta antibodyAnti-Nkg2d Ligand 1 antibodyAnti-N2dl-1 antibodyAnti-Nkg2dl1 antibodyAnti-Retinoic Acid Early Transcript 1i antibodyAnti-ULBP1 antibodyAnti-N2DL1 antibodyAnti-RAET1I antibody |
Information sourced from Uniprot.org