| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UGT8 |
| Gene ID: | 7368 |
| Uniprot ID: | CGT_HUMAN |
| Immunogen Region: | 380-460 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 380-460 of human UGT8 (NP_003351.2). |
| Immunogen Sequence: | FGDHYDTMTRVQAKGMGILL EWKTVTEKELYEALVKVINN PSYRQRAQKLSEIHKDQPGH PVNRTIYWIDYIIRHNGAHH L |
| Function | Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides. |
| Protein Name | 2-Hydroxyacylsphingosine 1-Beta-GalactosyltransferaseCeramide Udp-GalactosyltransferaseCerebroside SynthaseUdp-Galactose-Ceramide Galactosyltransferase |
| Database Links | Reactome: R-HSA-9840309 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-2-Hydroxyacylsphingosine 1-Beta-Galactosyltransferase antibodyAnti-Ceramide Udp-Galactosyltransferase antibodyAnti-Cerebroside Synthase antibodyAnti-Udp-Galactose-Ceramide Galactosyltransferase antibodyAnti-UGT8 antibodyAnti-CGT antibodyAnti-UGT4 antibody |
Information sourced from Uniprot.org