| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UGT8 (380-460) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UGT8 |
| Gene ID: |
7368 |
| Uniprot ID: |
CGT_HUMAN |
| Immunogen Region: |
380-460 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 380-460 of human UGT8 (NP_003351.2). |
| Immunogen Sequence: |
FGDHYDTMTRVQAKGMGILL EWKTVTEKELYEALVKVINN PSYRQRAQKLSEIHKDQPGH PVNRTIYWIDYIIRHNGAHH L |
| Function | Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides. |
| Protein Name | 2-Hydroxyacylsphingosine 1-Beta-GalactosyltransferaseCeramide Udp-GalactosyltransferaseCerebroside SynthaseUdp-Galactose-Ceramide Galactosyltransferase |
| Database Links | Reactome: R-HSA-1660662 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-2-Hydroxyacylsphingosine 1-Beta-Galactosyltransferase antibodyAnti-Ceramide Udp-Galactosyltransferase antibodyAnti-Cerebroside Synthase antibodyAnti-Udp-Galactose-Ceramide Galactosyltransferase antibodyAnti-UGT8 antibodyAnti-CGT antibodyAnti-UGT4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
